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Investigation of restriction-modification enzymes from M. varians RFL19 with a new type of specificity toward modification of substrate.

The characterization of MvaI restriction-modification enzymes, isolated from Micrococcus varians RFL19, is reported. Both enzymes recognize the 5'CC decreases (A/T)GG nucleotide sequence. The endonuclease cleaves the sequence at the position indicated by the arrow, whereas the methylase modifies the...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Butkus, V, Klimasauskas, S, Kersulyte, D, Vaitkevicius, D, Lebionka, A, Janulaitis, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1985
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.16.5727
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