The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease

BACKGROUND: In order to identify novel loci associated with Alzheimer's disease (AD), we conducted a genome-wide association study (GWAS) in the Spanish population. METHODS: We genotyped 1,128 individuals using the Affymetrix Nsp I 250K chip. A sample of 327 sporadic AD patients and 801 control...

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Detalhes bibliográficos
Main Authors: Antúnez, Carmen, Boada, Mercè, González-Pérez, Antonio, Gayán, Javier, Ramírez-Lorca, Reposo, Marín, Juan, Hernández, Isabel, Moreno-Rey, Concha, Morón, Francisco Jesús, López-Arrieta, Jesús, Mauleón, Ana, Rosende-Roca, Maitée, Noguera-Perea, Fuensanta, Legaz-García, Agustina, Vivancos-Moreau, Laura, Velasco, Juan, Carrasco, José Miguel, Alegret, Montserrat, Antequera-Torres, Martirio, Manzanares, Salvadora, Romo, Alejandro, Blanca, Irene, Ruiz, Susana, Espinosa, Anna, Castaño, Sandra, García, Blanca, Martínez-Herrada, Begoña, Vinyes, Georgina, Lafuente, Asunción, Becker, James T, Galán, José Jorge, Serrano-Ríos, Manuel, Vázquez, Enrique, Tárraga, Lluís, Sáez, María Eugenia, López, Oscar L, Real, Luis Miguel, Ruiz, Agustín
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219074/
https://ncbi.nlm.nih.gov/pubmed/21627779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm249
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