Optimal tumor sampling for immunostaining of biomarkers in breast carcinoma

INTRODUCTION: Biomarkers, such as Estrogen Receptor, are used to determine therapy and prognosis in breast carcinoma. Immunostaining assays of biomarker expression have a high rate of inaccuracy; for example, estimates are as high as 20% for Estrogen Receptor. Biomarkers have been shown to be hetero...

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Bibliographic Details
Main Authors: Tolles, Juliana, Bai, Yalai, Baquero, Maria, Harris, Lyndsay N, Rimm, David L, Molinaro, Annette M
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218938/
https://ncbi.nlm.nih.gov/pubmed/21592345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2882
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