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Notch signaling as a therapeutic target for breast cancer treatment?

Aberrant Notch signaling can induce mammary gland carcinoma in transgenic mice, and high expressions of Notch receptors and ligands have been linked to poor clinical outcomes in human patients with breast cancer. This suggests that inhibition of Notch signaling may be beneficial for breast cancer tr...

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Detalhes bibliográficos
Main Authors: Han, Jianxun, Hendzel, Michael J, Allalunis-Turner, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218932/
https://ncbi.nlm.nih.gov/pubmed/21672271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2875
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