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EZH2-mediated epigenetic repression of DNA repair in promoting breast tumor initiating cells

Members of the Polycomb-group (PcG) family of proteins, including EZH2 (enhancer of zeste homolog 2), are involved in establishing epigenetic silencing of developmental genes in adult and embryonic stem cells, and their deregulation has been implicated in cancer. In a recent report, EZH2-mediated ep...

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Bibliografische gegevens
Hoofdauteurs: Stefansson, Olafur Andri, Esteller, Manel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218929/
https://ncbi.nlm.nih.gov/pubmed/21672285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2871
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