Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model

INTRODUCTION: The aim of this prospective, randomized, controlled, double-blind study was to evaluate the effects of tiludronate (TLN), a bisphosphonate, on structural, biochemical and molecular changes and function in an experimental dog model of osteoarthritis (OA). METHODS: Baseline values were e...

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Detalhes bibliográficos
Main Authors: Moreau, Maxim, Rialland, Pascale, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Lajeunesse, Daniel, Boileau, Christielle, Caron, Judith, Frank, Diane, Lussier, Bertrand, del Castillo, Jerome RE, Beauchamp, Guy, Gauvin, Dominique, Bertaim, Thierry, Thibaud, Dominique, Troncy, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218913/
https://ncbi.nlm.nih.gov/pubmed/21693018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3373
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