An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations

We present an optimized probe design for copy number variation (CNV) and SNP genotyping in the Plasmodium falciparum genome. We demonstrate that variable length and isothermal probes are superior to static length probes. We show that sample preparation and hybridization conditions mitigate the effec...

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Detalhes bibliográficos
Main Authors: Tan, John C, Miller, Becky A, Tan, Asako, Patel, Jigar J, Cheeseman, Ian H, Anderson, Tim JC, Manske, Magnus, Maslen, Gareth, Kwiatkowski, Dominic P, Ferdig, Michael T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218861/
https://ncbi.nlm.nih.gov/pubmed/21477297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-4-r35
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