An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations

We present an optimized probe design for copy number variation (CNV) and SNP genotyping in the Plasmodium falciparum genome. We demonstrate that variable length and isothermal probes are superior to static length probes. We show that sample preparation and hybridization conditions mitigate the effec...

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Autores principales: Tan, John C, Miller, Becky A, Tan, Asako, Patel, Jigar J, Cheeseman, Ian H, Anderson, Tim JC, Manske, Magnus, Maslen, Gareth, Kwiatkowski, Dominic P, Ferdig, Michael T
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218861/
https://ncbi.nlm.nih.gov/pubmed/21477297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-4-r35
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