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What does biologically meaningful mean? A perspective on gene regulatory network validation

Gene regulatory networks (GRNs) are rapidly being delineated, but their quality and biological meaning are often questioned. Here, I argue that biological meaning is challenging to define and discuss reasons why GRN validation should be interpreted cautiously.

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Bibliografiske detaljer
Hovedforfatter: Walhout, Albertha JM
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218850/
https://ncbi.nlm.nih.gov/pubmed/21489330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-4-109
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