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Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy

BACKGROUND: Chromosomal aneuploidy, that is to say the gain or loss of chromosomes, is the most common abnormality in cancer. While certain aberrations, most commonly translocations, are known to be strongly associated with specific cancers and contribute to their formation, most aberrations appear...

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Detalhes bibliográficos
Main Authors: Ozery-Flato, Michal, Linhart, Chaim, Trakhtenbrot, Luba, Izraeli, Shai, Shamir, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218849/
https://ncbi.nlm.nih.gov/pubmed/21714908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-6-r61
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