Dynamics of mitochondrial heteroplasmy in three families investigated via a repeatable re-sequencing study

BACKGROUND: Originally believed to be a rare phenomenon, heteroplasmy - the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual - is emerging as an important component of eukaryotic genetic diversity. Heteroplasmies can be used as genetic markers in appli...

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Hlavní autoři: Goto, Hiroki, Dickins, Benjamin, Afgan, Enis, Paul, Ian M, Taylor, James, Makova, Kateryna D, Nekrutenko, Anton
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218847/
https://ncbi.nlm.nih.gov/pubmed/21699709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-6-r59
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