ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic regions

ZINBA (Zero-Inflated Negative Binomial Algorithm) identifies genomic regions enriched in a variety of ChIP-seq and related next-generation sequencing experiments (DNA-seq), calling both broad and narrow modes of enrichment across a range of signal-to-noise ratios. ZINBA models and accounts for facto...

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Detalhes bibliográficos
Main Authors: Rashid, Naim U, Giresi, Paul G, Ibrahim, Joseph G, Sun, Wei, Lieb, Jason D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218829/
https://ncbi.nlm.nih.gov/pubmed/21787385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-7-r67
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