The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease

Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase B (TrkB) are widely expressed in the vertebrate nervous system and play a central role in mature neuronal function. In vitro BDNF/TrkB signaling promotes neuronal survival and can help neurons resist toxic insults....

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Bibliographic Details
Main Authors: Zhai, Jinbin, Zhou, Weiguo, Li, Jian, Hayworth, Christopher R., Zhang, Lei, Misawa, Hidemi, Klein, Rudiger, Scherer, Steven S., Balice-Gordon, Rita J., Kalb, Robert Gordon
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218642/
https://ncbi.nlm.nih.gov/pubmed/21816949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr335
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