Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment

BACKGROUND: The formulation of docetaxel available for clinical use (Taxotere(®)) contains a high concentration of polysorbate 80 (Tween 80). After incorporation of Tween 80 into poly-ɛ-caprolactone (PCL)-Tween 80 copolymer, the relative amount of Tween 80 should be decreased and the advantages of P...

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Main Authors: Ma, Yuandong, Zheng, Yi, Zeng, Xiaowei, Jiang, Liqin, Chen, Hongbo, Liu, Ranyi, Huang, Laiqiang, Mei, Lin
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2011
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218581/
https://ncbi.nlm.nih.gov/pubmed/22114498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S25251
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