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Reexamining a proposal: Thymidylate synthase 5′-untranslated region as a regulator of translation efficiency
The DNA replicative gene, thymidylate synthase (TYMS), is inhibited upon treatment with the anticancer drug 5-fluorouracil (5-FU). TYMS has 28-bp tandem repeat sequences or VNTR (variable numbers of tandem repeats) in the 5′-untranslated region (5′-UTR). The number of these repeats is variable in an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3218528/ https://ncbi.nlm.nih.gov/pubmed/21811101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.8.16867 |
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