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Virtual screening of 2,3-disubstituted-4(3H)-quinazolinones possessing benzenesulfonamide moiety for COX-2 inhibitor

COX inhibitors which selectively inhibits the inducible COX-2 is an oenzyme that causes inflammation. They are clinically effective anti-inflammatory agents with less gastrointestinal and renal toxicity. However, they lack anti-thrombotic activity and hence lead to increased incidences of adverse ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hayun, Yanuar, Arry, Hanafi, Muhammad, PWS, Sumi Hudiyono
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biomedical Informatics 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218419/
https://ncbi.nlm.nih.gov/pubmed/22125393
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