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Substrate Stiffness Increases Twitch Power of Neonatal Cardiomyocytes in Correlation with Changes in Myofibril Structure and Intracellular Calcium

During neonatal development, there is an increase in myocardial stiffness that coincides with an increase in the contractility of the heart. In vitro assays have shown that substrate stiffness plays a role in regulating the twitch forces produced by immature cardiomyocytes. However, its effect on tw...

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Detalhes bibliográficos
Main Authors: Rodriguez, Anthony G., Han, Sangyoon J., Regnier, Michael, Sniadecki, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218322/
https://ncbi.nlm.nih.gov/pubmed/22098744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.057
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