Regulatory T Cells and IL-10 Independently Counterregulate Cytotoxic T Lymphocyte Responses Induced by Transcutaneous Immunization

BACKGROUND: The imidazoquinoline derivate imiquimod induces inflammatory responses and protection against transplanted tumors when applied to the skin in combination with a cognate peptide epitope (transcutaneous immunization, TCI). Here we investigated the role of regulatory T cells (T(reg)) and th...

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Detalhes bibliográficos
Main Authors: Stein, Pamela, Weber, Michael, Prüfer, Steve, Schmid, Beate, Schmitt, Edgar, Probst, Hans-Christian, Waisman, Ari, Langguth, Peter, Schild, Hansjörg, Radsak, Markus P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218067/
https://ncbi.nlm.nih.gov/pubmed/22114725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027911
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