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Protein Synthesis Attenuation by Phosphorylation of eIF2α Is Required for the Differentiation of Trypanosoma cruzi into Infective Forms

Chagas' disease is a potentially life-threatening illness caused by the unicellular protozoan parasite Trypanosoma cruzi. It is transmitted to humans by triatomine bugs where T. cruzi multiplies and differentiates in the digestive tract. The differentiation of proliferative and non-infective ep...

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Bibliographic Details
Main Authors: Tonelli, Renata R., Augusto, Leonardo da Silva, Castilho, Beatriz A., Schenkman, Sergio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218062/
https://ncbi.nlm.nih.gov/pubmed/22114724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027904
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