Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report

BACKGROUND: Aldosterone levels are elevated in a rat model of type 2 diabetes mellitus, the Zucker Diabetic fatty rat (ZDF). Moreover blood pressure in ZDF rats is salt-sensitive. The aim of this study was to examine the effect of the aldosterone antagonist eplerenone on structural and mechanical pr...

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Detalhes bibliográficos
Main Authors: Resch, Markus, Schmid, Peter, Amann, Kerstin, Fredersdorf, Sabine, Weil, Joachim, Schach, Christian, Birner, Christoph, Griese, Daniel P, Kreuzer, Peter, Brunner, Sabine, Luchner, Andreas, Riegger, Günter AJ, Endemann, Dierk H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217853/
https://ncbi.nlm.nih.gov/pubmed/22008236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-10-94
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