The Three-Layer Concentric Model of Glioblastoma: Cancer Stem Cells, Microenvironmental Regulation, and Therapeutic Implications

Tumors arising in the central nervous system are thought to originate from a sub-population of cells named cancer stem cells (CSCs) or tumor initiating cells (TICs) that possess an immature phenotype, combined with self-renewal and chemotherapy resistance capacity. Moreover, in the last years, these...

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Detalles Bibliográficos
Main Authors: Persano, Luca, Rampazzo, Elena, Della Puppa, Alessandro, Pistollato, Francesca, Basso, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
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Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217608/
https://ncbi.nlm.nih.gov/pubmed/22125441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2011/736480
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