Regulatory T cell expression of CLA or α(4)β(7) and skin or gut acute GVHD outcomes

Regulatory T cells (Tregs) are a suppressive subset of CD4(+) T lymphocytes implicated in the prevention of acute GVHD (aGVHD) after allo-SCT (ASCT). To determine whether increased frequency of Tregs with a skin-homing (cutaneous lymphocyte Ag, CLA(+)) or a gut-homing (α(4)β(7)(+)) phenotype is asso...

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Detalhes bibliográficos
Main Authors: Engelhardt, BG, Jagasia, M, Savani, BN, Bratcher, NL, Greer, JP, Jiang, A, Kassim, AA, Lu, P, Schuening, F, Yoder, SM, Rock, MT, Crowe, JE
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217583/
https://ncbi.nlm.nih.gov/pubmed/20577222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2010.127
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