Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia

Friend leukemia virus integration 1 (FLI1), an Ets transcription factor family member, is linked to acute myelogenous leukemia (AML) by chromosomal events at the FLI1 locus, but the biologic impact of FLI1 expression on AML is unknown. FLI1 protein expression was measured in 511 newly diagnosed AML...

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Hlavní autoři: Kornblau, Steven M., Qiu, Yi Hua, Zhang, Nianxiang, Singh, Neera, Faderl, Stefan, Ferrajoli, Alessandra, York, Heather, Qutub, Amina A., Coombes, Kevin R., Watson, Dennis K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217360/
https://ncbi.nlm.nih.gov/pubmed/21917756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-348052
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