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Candidate genes for panhypopituitarism identified by gene expression profiling
Mutations in the transcription factors PROP1 and PIT1 (POU1F1) lead to pituitary hormone deficiency and hypopituitarism in mice and humans. The dysmorphology of developing Prop1 mutant pituitaries readily distinguishes them from those of Pit1 mutants and normal mice. This and other features suggest...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3217323/ https://ncbi.nlm.nih.gov/pubmed/21828248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00080.2011 |
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