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Multistate proteomics analysis reveals novel strategies used by a hibernator to precondition the heart and conserve ATP for winter heterothermy

The hibernator's heart functions continuously and avoids damage across the wide temperature range of winter heterothermy. To define the molecular basis of this phenotype, we quantified proteomic changes in the 13-lined ground squirrel heart among eight distinct physiological states encompassing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grabek, Katharine R., Karimpour-Fard, Anis, Epperson, L. Elaine, Hindle, Allyson, Hunter, Lawrence E., Martin, Sandra L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217319/
https://ncbi.nlm.nih.gov/pubmed/21914784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00125.2011
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