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Multistate proteomics analysis reveals novel strategies used by a hibernator to precondition the heart and conserve ATP for winter heterothermy

The hibernator's heart functions continuously and avoids damage across the wide temperature range of winter heterothermy. To define the molecular basis of this phenotype, we quantified proteomic changes in the 13-lined ground squirrel heart among eight distinct physiological states encompassing...

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Detalhes bibliográficos
Main Authors: Grabek, Katharine R., Karimpour-Fard, Anis, Epperson, L. Elaine, Hindle, Allyson, Hunter, Lawrence E., Martin, Sandra L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217319/
https://ncbi.nlm.nih.gov/pubmed/21914784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00125.2011
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