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ANG II induces apoptosis of human vascular smooth muscle via extrinsic pathway involving inhibition of Akt phosphorylation and increased FasL expression

In addition to well-documented vascular growth-promoting effects, ANG II exerts proapoptotic effects that are poorly understood. IGF-1 is a potent survival factor for human vascular smooth muscle cells (hVSMC), and its antiapoptotic effects are mediated via the IGF-1 receptor (IGF-1R) through a sign...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Li, Yangxin, Song, Yao-Hua, Mohler, Jessica, Delafontaine, Patrick
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217239/
https://ncbi.nlm.nih.gov/pubmed/16339840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00551.2005
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