Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo

Neuroprotective properties of bilobalide, a specific constituent of Ginkgo extracts, were tested in a mouse model of stroke. After 24 hours of middle cerebral artery occlusion (MCAO), bilobalide reduced infarct areas in the core region (striatum) by 40-50% when given at 10 mg/kg one hour prior to MC...

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Detaylı Bibliyografya
Asıl Yazarlar: Lang, Dorothee, Kiewert, Cornelia, Mdzinarishvili, Alexander, Schwarzkopf, Tina Maria, Sumbria, Rachita, Hartmann, Joachim, Klein, Jochen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217178/
https://ncbi.nlm.nih.gov/pubmed/22032877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.10.005
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