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The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background
Mice homozygous for a mutation (Brdt(ΔBD1/ΔBD1)) lacking the first bromodomain of Brdt, a testis-specific member of the BET family of double-bromodomain containing proteins, are sterile and exhibit profound defects in chromatin remodeling during spermiogenesis. We have now observed that a prominent...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3217133/ https://ncbi.nlm.nih.gov/pubmed/22020252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.10.005 |
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