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DEVELOPMENTAL EXPOSURE TO ORGANOPHOSPHATES TRIGGERS TRANSCRIPTIONAL CHANGES IN GENES ASSOCIATED WITH PARKINSON’S DISEASE IN VITRO AND IN VIVO

Epidemiologic studies support a connection between organophosphate pesticide exposures and subsequent risk of Parkinson’s Disease (PD). We used differentiating, neuronotypic PC12 cells to compare organophosphates (chlorpyrifos, diazinon), an organochlorine (dieldrin) and a metal (Ni(2+)) for their e...

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Bibliografische gegevens
Hoofdauteurs: Slotkin, Theodore A., Seidler, Frederic J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217114/
https://ncbi.nlm.nih.gov/pubmed/21968025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2011.09.017
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