Toll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia

Microglia are the resident mononuclear phagocytes of the CNS parenchyma and represent an initial line of defense against invading microorganisms. Microglia utilize Toll-like receptors (TLRs) for pathogen recognition and TLR2 specifically senses conserved motifs of Gram-positive bacteria including li...

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Bibliografiska uppgifter
Huvudupphovsmän: Holley, Monica M., Zhang, Yongqing, Lehrmann, Elin, Wood, William H., Becker, Kevin G., Kielian, Tammy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217087/
https://ncbi.nlm.nih.gov/pubmed/21901759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21243
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