Quantifying the Importance of MSP1-19 as a Target of Growth-Inhibitory and Protective Antibodies against Plasmodium falciparum in Humans

BACKGROUND: Antibodies targeting blood stage antigens are important in protection against malaria, but the key targets and mechanisms of immunity are not well understood. Merozoite surface protein 1 (MSP1) is an abundant and essential protein. The C-terminal 19 kDa region (MSP1-19) is regarded as a...

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Main Authors: Wilson, Danny W., Fowkes, Freya J. I., Gilson, Paul R., Elliott, Salenna R., Tavul, Livingstone, Michon, Pascal, Dabod, Elija, Siba, Peter M., Mueller, Ivo, Crabb, Brendan S., Beeson, James G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217002/
https://ncbi.nlm.nih.gov/pubmed/22110733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027705
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