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Qilin Is Essential for Cilia Assembly and Normal Kidney Development in Zebrafish

Defects in the cilium, a once thought vestigial organelle, have recently been implicated in many human diseases, including a number of cystic kidney diseases such as polycystic kidney disease (PKD), Bardet Bieldl Syndrome, and Meckel-Gruber Syndrome. In a forward genetic screen, qilin was identified...

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Détails bibliographiques
Auteurs principaux: Li, Jade, Sun, Zhaoxia
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216947/
https://ncbi.nlm.nih.gov/pubmed/22102889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027365
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