Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

BACKGROUND: Despite their well-established functional roles, histone modifications have received less attention than DNA methylation in the cancer field. In order to evaluate their importance in colorectal cancer (CRC), we generated the first genome-wide histone modification profiles in paired norma...

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Main Authors: Enroth, Stefan, Rada-Iglesisas, Alvaro, Andersson, Robin, Wallerman, Ola, Wanders, Alkwin, Påhlman, Lars, Komorowski, Jan, Wadelius, Claes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216894/
https://ncbi.nlm.nih.gov/pubmed/22011431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-450
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