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NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II
The vasoactive peptide urotensin-II (U-II) has been associated with vascular remodeling in different cardiovascular disorders. Although U-II can induce reactive oxygen species (ROS) by the NADPH oxidase NOX4 and stimulate smooth muscle cell (SMC) proliferation, the precise mechanisms linking U-II to...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216667/ https://ncbi.nlm.nih.gov/pubmed/21965295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-12-0971 |
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