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Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization

Changes in blood flow regulate gene expression and protein synthesis in vascular endothelial cells, and this regulation is involved in the development of atherosclerosis. How mechanical stimuli are transmitted from the endothelial luminal surface to the nucleus is incompletely understood. The linker...

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Detalhes bibliográficos
Main Authors: Morgan, Joshua T., Pfeiffer, Emily R., Thirkill, Twanda L., Kumar, Priyadarsini, Peng, Gordon, Fridolfsson, Heidi N., Douglas, Gordon C., Starr, Daniel A., Barakat, Abdul I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216658/
https://ncbi.nlm.nih.gov/pubmed/21937718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0287
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