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Structural basis of the myosin X PH1(N)-PH2-PH1(C) tandem as a specific and acute cellular PI(3,4,5)P(3) sensor

Myosin X (MyoX) is an unconventional myosin that is known to induce the formation and elongation of filopodia in many cell types. MyoX-induced filopodial induction requires the three PH domains in its tail region, although with unknown underlying molecular mechanisms. MyoX's first PH domain is...

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Библиографические подробности
Главные авторы: Lu, Qing, Yu, Jiang, Yan, Jing, Wei, Zhiyi, Zhang, Mingjie
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216653/
https://ncbi.nlm.nih.gov/pubmed/21965296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0354
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