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Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor

Cholesterol influences ion-channel function, distribution and clustering in the membrane, endocytosis, and exocytic sorting of the nicotinic acetylcholine receptor (AChR). We report the occurrence of a cholesterol recognition motif, here coined “CARC”, in the transmembrane regions of AChR subunits t...

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Autori principali: Baier, Carlos J., Fantini, Jacques, Barrantes, Francisco J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216556/
https://ncbi.nlm.nih.gov/pubmed/22355588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00069
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