Cross-Reactivity and Expansion of Dengue-Specific T cells During Acute Primary and Secondary Infections in Humans

Serotype-cross-reactive memory T cells responding to secondary dengue virus (DENV) infection are thought to contribute to disease. However, epitope-specific T cell responses have not been thoroughly compared between subjects with primary versus secondary DENV infection. We studied CD8(+) T cells spe...

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Detalhes bibliográficos
Main Authors: Friberg, Heather, Bashyam, Hema, Toyosaki-Maeda, Tomoko, Potts, James A., Greenough, Thomas, Kalayanarooj, Siripen, Gibbons, Robert V., Nisalak, Ananda, Srikiatkhachorn, Anon, Green, Sharone, Stephens, Henry A. F., Rothman, Alan L., Mathew, Anuja
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216538/
https://ncbi.nlm.nih.gov/pubmed/22355570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00051
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