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Hyperthermic seizures and aberrant cellular homeostasis in Drosophila dystrophic muscles

In humans, mutations in the Dystrophin Glycoprotein Complex (DGC) cause muscular dystrophies (MDs) that are associated with muscle loss, seizures and brain abnormalities leading to early death. Using Drosophila as a model to study MD we have found that loss of Dystrophin (Dys) during development lea...

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Detalhes bibliográficos
Main Authors: Marrone, April K., Kucherenko, Mariya M., Wiek, Robert, Göpfert, Martin C., Shcherbata, Halyna R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216534/
https://ncbi.nlm.nih.gov/pubmed/22355566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00047
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