The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes

Background. Maternal alloantibodies against HPA-1a can cross placenta, opsonize foetal platelets, and induce neonatal alloimmune thrombocytopenia (NAIT). In a study of 100, 448 pregnant women in Norway during 1995–2004, 10.6% of HPA-1a negative women had detectable anti-HPA-1a antibodies. Design and...

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Detalhes bibliográficos
Main Authors: Ahlen, Maria Therese, Husebekk, Anne, Killie, Mette Kjær, Kjeldsen-Kragh, Jens, Olsson, Martin L., Skogen, Bjørn
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216343/
https://ncbi.nlm.nih.gov/pubmed/22110529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/156867
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