CpG Oligodeoxynucleotide and Montanide ISA 51 Adjuvant Combination Enhanced the Protective Efficacy of a Subunit Malaria Vaccine

Unmethylated CpG dinucleotide motifs present in bacterial genomes or synthetic oligodeoxynucleotides (ODNs) serve as strong immunostimulatory agents in mice, monkeys and humans. We determined the adjuvant effect of murine CpG ODN 1826 on the immunogenicity and protective efficacy of the Saccharomyce...

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Détails bibliographiques
Auteurs principaux: Kumar, Sanjai, Jones, Trevor R., Oakley, Miranda S., Zheng, Hong, Kuppusamy, Shanmuga P., Taye, Alem, Krieg, Arthur M., Stowers, Anthony W., Kaslow, David C., Hoffman, Stephen L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Fungal and Parasitic Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC321633/
https://ncbi.nlm.nih.gov/pubmed/14742540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.949-957.2004
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