Tumor necrosis factor and lymphotoxin-alpha genetic polymorphisms and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study of patients treated with BFM therapy

BACKGROUND: Circulating levels of tumor necrosis factor (TNF) and lymphotoxin-α (LT-α) have been associated with outcome in solid and hematologic malignancies. Within the TNF gene and the LT-α gene, polymorphisms have been identified at nucleotide positions -308 and +252, respectively. The variant a...

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Hlavní autoři: Stanulla, Martin, Schrauder, André, Welte, Karl, Schrappe, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2001
Témata:
Case Control Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC32163/
https://ncbi.nlm.nih.gov/pubmed/11319038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2326-1-2
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