A genetic polymorphism in the CAV1 gene associates with the development of bronchiolitis obliterans syndrome after lung transplantation

BACKGROUND: Caveolin 1 (Cav-1) is the primary structural component of cell membrane invaginations called 'caveolae'. Expression of Cav-1 is implicated in the pathogenesis of pulmonary fibrosis. Genetic polymorphisms in the CAV1 gene influence the function of Cav-1 in malignancies and assoc...

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Bibliografski detalji
Glavni autori: Kastelijn, Elisabeth A, van Moorsel, Coline HM, Kazemier, Karin M, Roothaan, Suzan M, Ruven, Henk JT, Kwakkel-van Erp, Johanna M, van de Graaf, Ed A, Zanen, Pieter, van Kessel, Diana A, Grutters, Jan C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215956/
https://ncbi.nlm.nih.gov/pubmed/22040717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-4-24
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