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Genetic Variation of the Alpha Subunit of the Epithelial Na(+) Channels Influences Exhaled Na(+) in Healthy Humans

Epithelial Na(+) Channels (ENaC) are located on alveolar cells and are important in β(2)-adrenergic receptor-mediated lung fluid clearance through the removal of Na(+) from the alveolar airspace. Previous work has demonstrated that genetic variation of the alpha subunit of ENaC at amino acid 663 is...

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Detalhes bibliográficos
Main Authors: Foxx-Lupo, William T., Wheatley, Courtney M., Baker, Sarah E., Cassuto, Nicholas A., Delamere, Nicholas A., Snyder, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215916/
https://ncbi.nlm.nih.gov/pubmed/21889619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2011.08.008
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