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Rac1 GTPase -deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival
Morphogenesis and shape of the ocular lens depend on epithelial cell elongation and differentiation into fiber cells, followed by the symmetric and compact organization of fiber cells within an enclosed extracellular matrix-enriched elastic capsule. The cellular mechanisms orchestrating these differ...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215831/ https://ncbi.nlm.nih.gov/pubmed/21945075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.09.004 |
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