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A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death

Tumor necrosis factor (TNF) plays a dual role in neurodegenerative diseases. Whereas TNF receptor (TNFR) 1 is predominantly associated with neurodegeneration, TNFR2 is involved in tissue regeneration and neuroprotection. Accordingly, the availability of TNFR2-selective agonists could allow the devel...

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Main Authors: Fischer, Roman, Maier, Olaf, Siegemund, Martin, Wajant, Harald, Scheurich, Peter, Pfizenmaier, Klaus
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215731/
https://ncbi.nlm.nih.gov/pubmed/22110694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027621
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