Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure

BACKGROUND: Small molecule ligands often have multiple effects on the transcriptional program of a cell: they trigger a receptor specific response and additional, indirect responses ("side effects"). Distinguishing those responses is important for understanding side effects of drugs and fo...

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Autori principali: Michaelson, Jacob J, Trump, Saskia, Rudzok, Susanne, Gräbsch, Carolin, Madureira, Danielle J, Dautel, Franziska, Mai, Juliane, Attinger, Sabine, Schirmer, Kristin, von Bergen, Martin, Lehmann, Irina, Beyer, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215681/
https://ncbi.nlm.nih.gov/pubmed/21995607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-502
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