Genotyping of Plasmodium falciparum Pyrimethamine Resistance by Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry

Increasing resistance, recrudescences, and treatment failure have led to the replacement of chloroquine with the combination of pyrimethamine (PYR) and sulfadoxine (SDX) as the first-line antimalarial drugs for treatment of uncomplicated Plasmodium falciparum malaria in several areas where this dise...

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Detalhes bibliográficos
Main Authors: Marks, Florian, Meyer, Christian G., Sievertsen, Jürgen, Timmann, Christian, Evans, Jennifer, Horstmann, Rolf D., May, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321558/
https://ncbi.nlm.nih.gov/pubmed/14742196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.466-472.2004
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