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Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility

The retinoic acid receptor (RAR) is a member of the nuclear receptor superfamily. This ligand-inducible transcription factor binds to DNA as a heterodimer with the retinoid X receptor (RXR) in the nucleus. The nucleus is a dynamic compartment and live-cell imaging techniques make it possible to inve...

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Autori principali: Brazda, Peter, Szekeres, Tibor, Bravics, Balázs, Tóth, Katalin, Vámosi, György, Nagy, Laszlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215574/
https://ncbi.nlm.nih.gov/pubmed/22045737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.086082
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