Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir

Four newly synthesized ether lipid esters of cidofovir (CDV), hexadecyloxypropyl-CDV (HDP-CDV), octadecyloxyethyl-CDV (ODE-CDV), oleyloxypropyl-CDV (OLP-CDV), and oleyloxyethyl-CDV (OLE-CDV), were found to have enhanced activities against vaccinia virus (VV) and cowpox virus (CV) in vitro compared t...

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Detalhes bibliográficos
Main Authors: Quenelle, Debra C., Collins, Deborah J., Wan, W. Brad, Beadle, James R., Hostetler, Karl Y., Kern, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321539/
https://ncbi.nlm.nih.gov/pubmed/14742188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.404-412.2004
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