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Probing ribosomal protein–RNA interactions with an external force

Ribosomal (r-) RNA adopts a well-defined structure within the ribosome, but the role of r-proteins in stabilizing this structure is poorly understood. To address this issue, we use optical tweezers to unfold RNA fragments in the presence or absence of r-proteins. Here, we focus on Escherichia coli r...

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Autors principals: Mangeol, Pierre, Bizebard, Thierry, Chiaruttini, Claude, Dreyfus, Marc, Springer, Mathias, Bockelmann, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215066/
https://ncbi.nlm.nih.gov/pubmed/22025688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107121108
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